Half-Life Reference

Look up elimination half-lives, time to steady state, and dosing frequency for common compounds.

Half-life values are approximate. Many research compounds lack formal human pharmacokinetic studies. Estimated values are noted. This is reference data, not dosing guidance.

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AOD-9604	~1–2 hours (estimated)Estimated — limited human PK data available.	~6–10 hoursEstimated — limited human PK data available.	Once daily

BPC-157	~4 hours	~20 hours	1–2× daily

CJC-1295 (DAC)	~8 days	~4–5 weeks	1–2× weekly

CJC-1295 (no DAC / Mod GRF)	~30 minutes	~2.5 hours	1–3× daily

GHK-Cu	~1–2 hours (estimated)Estimated — limited human PK data available.	~6–10 hoursEstimated — limited human PK data available.	Once daily

Ipamorelin	~2 hours	~10 hours	1–3× daily

MK-677	~24 hours	~5 days	Once daily

NAD+ (IV)	~30–45 minutes (plasma)Estimated — limited human PK data available.	N/A	Per protocol

Oxytocin	~3–5 minutes (IV)	N/A	Per protocol

PT-141	~2–3 hours	~12–15 hours	As needed

Semaglutide	~7 days	~4–5 weeks	Once weekly

Sermorelin	~10–20 minutes	~1–2 hours	Once daily (before bed)

TB-500	~2–3 hours (estimated)Estimated — limited human PK data available.	~12–15 hoursEstimated — limited human PK data available.	2× weekly (loading), 1× weekly (maintenance)

Tesamorelin	~26–38 minutes	~3 hours	Once daily

Tirzepatide	~5 days	~4–5 weeks	Once weekly

Half-life

~1–2 hours (estimated)Estimated — limited human PK data available.

Steady state

~6–10 hoursEstimated — limited human PK data available.

Typical frequency

Once daily

Half-life

~4 hours

Steady state

~20 hours

Typical frequency

1–2× daily

Half-life

~8 days

Steady state

~4–5 weeks

Typical frequency

1–2× weekly

Half-life

~30 minutes

Steady state

~2.5 hours

Typical frequency

1–3× daily

Half-life

~1–2 hours (estimated)Estimated — limited human PK data available.

Steady state

~6–10 hoursEstimated — limited human PK data available.

Typical frequency

Once daily

Half-life

~2 hours

Steady state

~10 hours

Typical frequency

1–3× daily

Half-life

~24 hours

Steady state

~5 days

Typical frequency

Once daily

Half-life

~30–45 minutes (plasma)Estimated — limited human PK data available.

Steady state

N/A

Typical frequency

Per protocol

Half-life

~3–5 minutes (IV)

Steady state

N/A

Typical frequency

Per protocol

Half-life

~2–3 hours

Steady state

~12–15 hours

Typical frequency

As needed

Half-life

~7 days

Steady state

~4–5 weeks

Typical frequency

Once weekly

Half-life

~10–20 minutes

Steady state

~1–2 hours

Typical frequency

Once daily (before bed)

Half-life

~2–3 hours (estimated)Estimated — limited human PK data available.

Steady state

~12–15 hoursEstimated — limited human PK data available.

Typical frequency

2× weekly (loading), 1× weekly (maintenance)

Half-life

~26–38 minutes

Steady state

~3 hours

Typical frequency

Once daily

Half-life

~5 days

Steady state

~4–5 weeks

Typical frequency

Once weekly